#Taurine pregnancy free#

retinopathy, neuropathy, nephropathy, cardiomyopathy, platelet aggregation, endothelial dysfunction and atherosclerosis. There are no known safe limits of supplemental taurine during pregnancy, and no studies have examined the interactions of taurine with other chemicals.

When considering the clinical complications in diabetes, several links can be established between altered taurine metabolism and the development of cellular dysfunctions in diabetes which cause the clinical complications observed in diabetes, e.g. Intracellular accumulation of sorbitol is most likely to cause depletion of other intracellular compounds including osmolytes such as myo-inositol and taurine. In diabetes, the high extracellular levels of glucose disturb the cellular osmoregulation and sorbitol is formed intracellularly due to the intracellular polyol pathway, which is suspected to be one of the key processes in the development of diabetic late complications and associated cellular dysfunctions.

The C57BL/6 mouse strain is widely used in diabetic and atherosclerotic animal models.

#Taurine pregnancy free#

In human milk, taurine is the most abundant free amino acid (40. 27 Taurine is stored in the maternal tissues in early pregnancy for later transfer to the fetus in order to satisfy the needs of the fetus and the suckling infant for this amino acid. Some animals, such as the cat and the C57BL/6 mouse, have disturbances in taurine homeostasis. Also, due to the immature kidney in neonates, there is a relative inability to conserve taurine. in bile acid formation, as an osmolyte by cell volume regulation, in the heart, in the retina, in the formation of N-chlorotaurine by reaction with hypochlorous acid in leucocytes, and possibly for intracellular scavenging of carbonyl groups. The ubiquitously found beta-amino acid taurine has several physiological functions, e.g.